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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CISH All Species: 32.12
Human Site: S113 Identified Species: 70.67
UniProt: Q9NSE2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NSE2 NP_037456.5 258 28663 S113 V R D S T H P S Y L F T L S V
Chimpanzee Pan troglodytes XP_526202 462 50560 S317 V R D S T H P S Y L F T L S V
Rhesus Macaque Macaca mulatta XP_001097824 258 28705 S113 V R D S T H P S Y L F T L S V
Dog Lupus familis XP_541873 376 41170 S232 V R D S T H P S Y L F T L S V
Cat Felis silvestris
Mouse Mus musculus Q62225 257 28518 S113 V R D S T H P S Y L F T L S V
Rat Rattus norvegicus O70512 256 28380 S112 V R D S T H P S Y L F T L S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513494 261 29787 S122 V R D S T H P S Y L F T L S V
Chicken Gallus gallus Q9PW70 249 28100 S115 V R D S T H P S Y L F T L S V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001070085 212 23910 P81 L I R D S S H P D Y M L T L S
Tiger Blowfish Takifugu rubipres NP_001107630 214 24036 T83 N H P K H M L T L S V K T C C
Fruit Fly Dros. melanogaster Q08012 211 24417 G80 L L S N K H E G A F L I R I S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.6 96.5 62.2 N.A. 90.6 89.9 N.A. 67 67 N.A. 41 37.6 22 N.A. N.A. N.A.
Protein Similarity: 100 55.6 97.2 63.5 N.A. 92.2 91.4 N.A. 76.6 75.9 N.A. 54.6 48.8 34.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 0 0 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 N.A. 13.3 6.6 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % C
% Asp: 0 0 73 10 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 73 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 10 82 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 10 0 10 0 % I
% Lys: 0 0 0 10 10 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 19 10 0 0 0 0 10 0 10 73 10 10 73 10 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 73 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 73 10 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 10 73 10 10 0 73 0 10 0 0 0 73 19 % S
% Thr: 0 0 0 0 73 0 0 10 0 0 0 73 19 0 0 % T
% Val: 73 0 0 0 0 0 0 0 0 0 10 0 0 0 73 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 73 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _